I-Tolvaptan CAS 150683-30-0 API Factory High Quality

Inkcazelo emfutshane:

Igama leMichiza: iTolvaptan

CAS: 150683-30-0

Uvavanyo (HPLC): 98.0 ~ 102.0%

Imbonakalo: Mhlophe ukuya kuMhlophe-Obumhlophe obuyiCrystalline Powder

I-vasopressin enamandla kunye ekhethiweyo ye-vasopressin V2 i-receptor antagonist

Umgangatho ophezulu we-API, iMveliso yoRhwebo

Umbuzo: alvin@ruifuchem.com


Iinkcukacha zeMveliso

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Inkcazo:

Ubonelelo lwabavelisi
Umgangatho ophezulu, iMveliso yoRhwebo
Igama leMichiza: iTolvaptan
CAS: 150683-30-0

Iipropati zeMichiza:

Igama eTolvaptan
Igama leMchiza N-[4-(9-chloro-6-hydroxy-2-azabicyclo[5.4.0]undeca-8,10,12-triene-2-carbonyl)-3-methyl-phenyl]-2-methyl-benzamide
Inombolo yeCAS 150683-30-0
Inombolo yeCAT RF-API101
Ubume beStokhwe Kwi-Stock, iMveliso yeMveliso ukuya kwiiToni
Ifomula yeemolekyuli I-C26H25ClN2O3
Ubunzima beMolekyuli 448.94
Uphawu Ruifu Chemical

Iinkcukacha:

Into Iinkcukacha
Imbonakalo Mhlophe ukuya kuMhlophe-Mhlophe wePowder
Iindlela zokuchongwa IR, HPLC
Uvavanyo (HPLC) 98.0 ~ 102.0% (kwisiseko se-anhydrous)
Indawo yokunyibilika 219.0 ~ 222.0℃
Ilahleko ekomisweni ≤0.50%
Intsalela kwi-Ignition ≤0.10%
Ukungacoceki Okukodwa ≤0.50%
Ukungcola ngokupheleleyo ≤1.0%
Iintsimbi ezinzima ≤20ppm
Izinyibilikisi ezishiyekileyo Hlangana neNkcazo
Umgangatho woVavanyo Umgangatho woShishino
Ukusetyenziswa AbaPhakathi bamayeza

Ukupakishwa kunye noGcino:

Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi.

Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ukukhanya kunye nokufuma.

Izinto eziluncedo:

1

FAQ:

Isicelo:

I-Tolvaptan (i-CAS 150683-30-0), eyaziwa ngokuba yi-OPC-41061, i-arginine ekhuphisana ne-arginine i-vasopressin receptor 2 antagonist esetyenziselwa ukunyanga i-hyponatremia (izinga eliphantsi le-sodium yegazi) ehambelana nokungaphumeleli kwentliziyo, i-cirrhosis, kunye nesifo esingafanelekanga. ihomoni ye-antidiuretic (SIADH).I-Otsuka Pharmaceutical inelayisensi ye-tolvaptan phantsi kwegama lorhwebo i-Samsca emva kokuba i-FDA ivume ichiza ngoMeyi ka-2009.Kulingo lwe-2004, i-tolvaptan elawulwa nge-diuretics yendabuko yaphawulwa ukuba yandise ukukhutshwa kwamanzi amaninzi kunye nokuphucula amanqanaba e-sodium yegazi kwizigulane ezinentliziyo engaphumeleliyo ngaphandle kokuvelisa iziphumo ezinobungozi ezifana ne-hypotension (uxinzelelo lwegazi oluphantsi) okanye i-hypokalemia (ukunciphisa amanqanaba egazi e-potassium).Ichiza kwakhona alibonisi ziphumo zibi ekusebenzeni kwezintso.

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