I-2-Methyl-4-Nitrobenzoic Acid CAS 1975-51-5 iTolvaptan ePhakathi yeFactory ePhakamileyo

Inkcazelo emfutshane:

Igama leKhemikhali: 2-Methyl-4-Nitrobenzoic Acid

CAS: 1975-51-5

Ubunyulu: ≥98.0% (HPLC)

Imbonakalo: Phantse uMhlophe oMhlophe okanye oMthubi oMthubi wePowder

Phakathi kweTolvaptan (CAS 150683-30-0) yonyango lwe-Hyponatremia

Umbuzo: alvin@ruifuchem.com


Iinkcukacha zeMveliso

Iimveliso ezinxulumeneyo

Iithegi zeMveliso

Inkcazo:

Iipropati zeMichiza:

Igama leMchiza I-2-Methyl-4-Nitrobenzoic Acid
Izithethantonye I-4-Nitro-o-Toluic Acid;I-4-Nitro-2-Methylbenzoic Acid
Inombolo yeCAS 1975-51-5
Inombolo yeCAT RF-PI397
Ubume beStokhwe Kwi-Stock, iMveliso yeMveliso ukuya kwiiToni
Ifomula yeemolekyuli C8H7NO4
Ubunzima beMolekyuli 181.15
Uphawu Ruifu Chemical

Iinkcukacha:

Into Iinkcukacha
Imbonakalo Phantse uMhlophe okanye uMthubi oMthubi wePowder
1H-NMR Ngokungqinelana noLwakhiwo
Ubunyulu / Indlela yokuHlalutya ≥98.0% (HPLC)
Indawo yokunyibilika 153.0 ~ 156.0℃
Ukufuma (KF) ≤0.50%
Intsalela kwi-Ignition ≤0.50%
Ukungcola ngokupheleleyo ≤2.0%
Umgangatho woVavanyo Umgangatho woShishino
Ukusetyenziswa Phakathi kweTolvaptan (CAS 150683-30-0)

Ukupakishwa kunye noGcino:

Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi.

Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ukukhanya kunye nokufuma.

Izinto eziluncedo:

1

FAQ:

Isicelo:

I-2-Methyl-4-Nitrobenzoic Acid (i-CAS 1975-51-5) isetyenziswe njenge-pharmaceutical intermediate kwi-synthesis ye-Tolvaptan (i-CAS 150683-30-0).I-Tolvaptan yinto ekhethiweyo, ekhuphisana ne-arginine i-vasopressin receptor 2 i-antagonist kunye ne-IC50 ye-1.28μM yokuthintela i-AVP-induced platelet aggregation.I-Tolvaptan isetyenziselwa ukunyanga i-hyponatremia (amanqanaba e-sodium ephantsi yegazi) ehambelana nokungaphumeleli kwentliziyo, i-cirrhosis, kunye ne-syndrome ye-antidiuretic hormone engafanelekanga (SIADH).I-Tolvaptan yamkelwa yi-US Food and Drug Administration ngoMeyi 19, 2009, kwaye ithengiswa yi-Otsuka Pharmaceutical Co. phantsi kwegama lezorhwebo elithi Samsca.

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